Single translation for many locales

Greetings to everyone,

Is it possible to do make a single translation for many locales? Let me explain it better: Can I create a single translation file for my theme called es.po and es.mo so it matches all possible variants for locales of the Spanish language? (i.e. es_ES, es_MX, etc.)

The idea here is to avoid copying the file several time to match all locales of the Spanish language.