WP_HOME (and WP_URL) are undefined

My site's working, but there's a cannot complete a loopback request error in the (dashboard) Tools/Site_Health window I'm tracking down.

My installation is in a subdirectory on my server: /home/public_html/my-site/wordpress

I have, in my (dashboard) Settings/General window:

WordPress Address (URL) https://my-site/wordpress and Site Address (URL) https://my-site

BUT: this doesn't agree with the WordPress Constants listed in the (dashboard) Tools/Site_Health (info) window: ABSPATH /home/public_html/my-site/wordpress/ and WP_HOME Undefined and WP_SITEURL Undefined

Any clues as to how to make WordPress globally aware of these settings?